CDC42EP5 anticorps (AA 1-50)
Aperçu rapide pour CDC42EP5 anticorps (AA 1-50) (ABIN1534743)
Antigène
Voir toutes CDC42EP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-50
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Fonction
- Cdc42EP5 Antibody
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Specificité
- Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human BORG3. AA range:1-50
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))
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Autre désignation
- BORG3
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Sujet
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Synonyms: CDC42EP5, BORG3, CEP5, Cdc42 effector protein 5, Binder of Rho GTPases 3
Background: Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins.The protein encoded byThis gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013],
Gene Name: CDC42EP5
Protein Name: Cdc42 effector protein 5
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Poids moléculaire
- 15 kDa
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ID gène
- 148170
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OMIM
- 609171
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UniProt
- Q6NZY7
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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