CLDN8 anticorps (AA 81-130)

N° du produit ABIN1534783

L’anticorps anti-CLDN8 Polyclonal Lapin est utilisé pour la détection de CLDN8 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour CLDN8 anticorps (AA 81-130) (ABIN1534783)

Antigène: CLDN8 (Claudin 8 (CLDN8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLDN8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CLDN8 anticorps

Épitope: AA 81-130

Fonction: Claudin-8 Antibody

Specificité: Claudin-8 Polyclonal Antibody detects endogenous levels of Claudin-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CLDN8. AA range:81-130

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CLDN8

Antigène: CLDN8 (Claudin 8 (CLDN8))

Autre désignation: CLDN8

Sujet:

Synonyms: CLDN8, Claudin-8

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010],

Gene Name: CLDN8

Protein Name: Claudin-8

Poids moléculaire: 24 kDa

ID gène: 9073

OMIM: 611231

UniProt: P56748

Pathways: Hepatitis C