Desmoglein 2 anticorps (AA 401-450)

N° du produit ABIN1534829

Cet anticorps anti-Desmoglein 2 Polyclonal Lapin (ABIN1534829) détecte spécifiquement Desmoglein 2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Desmoglein 2 anticorps (AA 401-450) (ABIN1534829)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Desmoglein 2 anticorps

Épitope: AA 401-450

Fonction: Dsg2 Antibody

Specificité: Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: DSG2

Sujet:

Synonyms: DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],

Gene Name: DSG2

Protein Name: Desmoglein-2

Poids moléculaire: 122 kDa

ID gène: 1829

OMIM: 125671

UniProt: Q14126

Pathways: Cell-Cell Junction Organization