DMGDH anticorps (AA 817-866)

N° du produit ABIN1534834

L’anticorps anti-DMGDH Polyclonal Lapin est utilisé pour la détection de DMGDH dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour DMGDH anticorps (AA 817-866) (ABIN1534834)

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMGDH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-DMGDH anticorps

Épitope: AA 817-866

Fonction: DMGDH Antibody

Specificité: DMGDH Polyclonal Antibody detects endogenous levels of DMGDH protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DMGDH

Antigène: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Autre désignation: DMGDH

Sujet:

Synonyms: DMGDH, Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH

Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Gene Name: DMGDH

Protein Name: Dimethylglycine dehydrogenase mitochondrial

Poids moléculaire: 96 kDa

ID gène: 29958

OMIM: 605849

UniProt: Q9UI17