GABRD anticorps (AA 141-190)
Aperçu rapide pour GABRD anticorps (AA 141-190) (ABIN485541)
Antigène
Voir toutes GABRD AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 141-190
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Fonction
- GABAA Rδ Antibody
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Specificité
- GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- GABRD (GABA A Receptor delta (GABRD))
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Autre désignation
- GABRD
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Sujet
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Synonyms: GABRD, Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit delta
Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho.This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Gene Name: GABRD
Protein Name: Gamma-aminobutyric acid receptor subunit delta
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Poids moléculaire
- 50 kDa
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ID gène
- 2563
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OMIM
- 137163
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UniProt
- O14764
Antigène
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