IQCB1 anticorps (AA 431-480)
Aperçu rapide pour IQCB1 anticorps (AA 431-480) (ABIN1534993)
Antigène
Voir toutes IQCB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 431-480
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Fonction
- Nephrocystin-5 Antibody
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Specificité
- Nephrocystin-5 Polyclonal Antibody detects endogenous levels of Nephrocystin-5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- IQCB1 (IQ Motif Containing B1 (IQCB1))
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Autre désignation
- IQCB1
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Sujet
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Synonyms: IQCB1, KIAA0036, NPHP5, OK/SW-cl.85, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ
Background: This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016],
Gene Name: IQCB1
Protein Name: IQ calmodulin-binding motif-containing protein 1
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Poids moléculaire
- 68 kDa
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ID gène
- 9657
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OMIM
- 609237
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UniProt
- Q15051
Antigène
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