LRRC41 anticorps (AA 391-440)

N° du produit ABIN1535000

Cet anticorps anti-LRRC41 Polyclonal Lapin (ABIN1535000) détecte spécifiquement LRRC41 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour LRRC41 anticorps (AA 391-440) (ABIN1535000)

Antigène: LRRC41 (Leucine Rich Repeat Containing 41 (LRRC41))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC41 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-LRRC41 anticorps

Épitope: AA 391-440

Fonction: LRRC41 Antibody

Specificité: LRRC41 Polyclonal Antibody detects endogenous levels of LRRC41 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human LRRC41. AA range:391-440

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur LRRC41

Antigène: LRRC41 (Leucine Rich Repeat Containing 41 (LRRC41))

Autre désignation: LRRC41

Sujet:

Synonyms: LRRC41, MUF1, PP7759, Leucine-rich repeat-containing protein 41, Protein Muf1

Background: caution:It is uncertain whether Met-1 or Met-23 is the initiator.,domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV].,function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification, protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally extended.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS(LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2.,

Gene Name: LRRC41

Protein Name: Leucine-rich repeat-containing protein 41

Poids moléculaire: 88 kDa

ID gène: 10489

UniProt: Q15345