LAMP3 anticorps (AA 274-323)

N° du produit ABIN1535014

L’anticorps anti-LAMP3 Polyclonal Lapin est utilisé pour la détection de LAMP3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF (p) et IHC (p).

Aperçu rapide pour LAMP3 anticorps (AA 274-323) (ABIN1535014)

Antigène: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAMP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LAMP3 anticorps

Épitope: AA 274-323

Fonction: DC-LAMP Antibody

Specificité: DC-LAMP Polyclonal Antibody detects endogenous levels of DC-LAMP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human LAMP3. AA range:274-323

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur LAMP3

Antigène: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Autre désignation: LAMP3

Sujet:

Synonyms: LAMP3, DCLAMP, TSC403, Lysosome-associated membrane glycoprotein 3, LAMP-3, Lysosomal-associated membrane protein 3, DC-lysosome-associated membrane glycoprotein, DC LAMP, Protein TSC403, CD antigen CD208

Background: MET proto-oncogene, receptor tyrosine kinase(MET) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],

Gene Name: LAMP3

Protein Name: Lysosome-associated membrane glycoprotein 3

Poids moléculaire: 44 kDa

OMIM: 605883

UniProt: Q9UQV4