Nesprin3 anticorps (AA 169-218)

N° du produit ABIN1535082

Cet anticorps Lapin Polyclonal détecte spécifiquement Nesprin3 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Nesprin3 anticorps (AA 169-218) (ABIN1535082)

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nesprin3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-Nesprin3 anticorps

Épitope: AA 169-218

Fonction: Nesprin-3 Antibody

Specificité: Nesprin-3 Polyclonal Antibody detects endogenous levels of Nesprin-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Nesprin3

Antigène: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Autre désignation: C14orf49

Sujet:

Synonyms: SYNE3, C14orf49, Nesprin-3, Nuclear envelope spectrin repeat protein 3

Background: function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity:Belongs to the nesprin family.,similarity:Contains 1 KASH domain.,similarity:Contains 2 spectrin repeats.,subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells.,subunit:Interacts with actin-binding domain of PLEC1/plectin.,

Gene Name: SYNE3

Protein Name: Nesprin-3

Poids moléculaire: 112 kDa

ID gène: 161176

OMIM: 610861

UniProt: Q6ZMZ3

Pathways: Maintenance of Protein Location