NREP anticorps (AA 13-62)

N° du produit ABIN1535102

Cet anticorps anti-NREP Polyclonal Lapin (ABIN1535102) détecte spécifiquement NREP dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NREP anticorps (AA 13-62) (ABIN1535102)

Antigène: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NREP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-NREP anticorps

Épitope: AA 13-62

Fonction: P311 Antibody

Specificité: P311 Polyclonal Antibody detects endogenous levels of P311 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human C5orf13. AA range:13-62

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NREP

Antigène: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Autre désignation: C5orf13

Sujet:

Synonyms: NREP, C5orf13, P311, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311

Background: P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability, the gene encoding P311 maps to human chromosome 5q22.

Gene Name: NREP

Protein Name: Neuronal regeneration-related protein

Poids moléculaire: 7 kDa

ID gène: 9315

OMIM: 607332

UniProt: Q16612