SESN1 anticorps (AA 271-320)

N° du produit ABIN1535359

L’anticorps anti-SESN1 Polyclonal Lapin est utilisé pour la détection de SESN1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour SESN1 anticorps (AA 271-320) (ABIN1535359)

Antigène: SESN1 (Sestrin 1 (SESN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SESN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SESN1 anticorps

Épitope: AA 271-320

Fonction: PA26 Antibody

Specificité: PA26 Polyclonal Antibody detects endogenous levels of PA26 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human SESN1. AA range:271-320

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SESN1

Antigène: SESN1 (Sestrin 1 (SESN1))

Autre désignation: SESN1

Sujet:

Synonyms: SESN1, PA26, SEST1, Sestrin-1, p53-regulated protein PA26

Background: This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],

Gene Name: SESN1

Protein Name: Sestrin-1

Poids moléculaire: 56 kDa

ID gène: 27244

OMIM: 606103

UniProt: Q9Y6P5