TMC8 anticorps (AA 601-650)
Aperçu rapide pour TMC8 anticorps (AA 601-650) (ABIN1535426)
Antigène
Voir toutes TMC8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 601-650
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Fonction
- TMC8 Antibody
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Specificité
- TMC8 Polyclonal Antibody detects endogenous levels of TMC8 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human TMC8. AA range:601-650
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- TMC8 (Transmembrane Channel-Like 8 (TMC8))
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Autre désignation
- TMC8
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Sujet
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Synonyms: TMC8, EVER2, EVIN2, Transmembrane channel-like protein 8, Epidermodysplasia verruciformis protein 2
Background: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels.This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008],
Gene Name: TMC8
Protein Name: Transmembrane channel-like protein 8
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Poids moléculaire
- 81 kDa
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ID gène
- 147138
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OMIM
- 226400
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UniProt
- Q8IU68
Antigène
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