UGDH anticorps (AA 391-440)

N° du produit ABIN1535450

Cet anticorps anti-UGDH Polyclonal Lapin (ABIN1535450) détecte spécifiquement UGDH dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour UGDH anticorps (AA 391-440) (ABIN1535450)

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGDH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-UGDH anticorps

Épitope: AA 391-440

Fonction: UDP-GlcDH Antibody

Specificité: UDP-GlcDH Polyclonal Antibody detects endogenous levels of UDP-GlcDH protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human UGDH. AA range:391-440

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur UGDH

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Autre désignation: UGDH

Sujet:

Synonyms: UGDH, UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH

Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],

Gene Name: UGDH

Protein Name: UDP-glucose 6-dehydrogenase

Poids moléculaire: 55 kDa

ID gène: 7358

OMIM: 603370

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process