Muscarinic Acetylcholine Receptor M2 anticorps (AA 185-234)
Aperçu rapide pour Muscarinic Acetylcholine Receptor M2 anticorps (AA 185-234) (ABIN1535645)
Antigène
Voir toutes Muscarinic Acetylcholine Receptor M2 (CHRM2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 185-234
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Fonction
- mAChR M2 Antibody
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Specificité
- MAChR M2 Polyclonal Antibody detects endogenous levels of mAChR M2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CHRM2. AA range:185-234
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
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Autre désignation
- CHRM2
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Sujet
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Synonyms: CHRM2, Muscarinic acetylcholine receptor M2
Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: CHRM2
Protein Name: Muscarinic acetylcholine receptor M2
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Poids moléculaire
- 51 kDa
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ID gène
- 1129
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OMIM
- 118493
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UniProt
- P08172
Antigène
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