GALR2 anticorps (AA 201-250)

N° du produit ABIN1535690

Cet anticorps anti-GALR2 Polyclonal Lapin (ABIN1535690) détecte spécifiquement GALR2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GALR2 anticorps (AA 201-250) (ABIN1535690)

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GALR2 anticorps

Épitope: AA 201-250

Fonction: GALR2 Antibody

Specificité: GALR2 Polyclonal Antibody detects endogenous levels of GALR2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human GALR2. AA range:201-250

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GALR2

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Autre désignation: GALR2

Sujet:

Synonyms: GALR2, GALNR2, Galanin receptor type 2, GAL2-R, GALR-2

Background: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul

Gene Name: GALR2

Protein Name: Galanin receptor type 2

Poids moléculaire: 41 kDa

ID gène: 8811

OMIM: 603691

UniProt: O43603

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour