Latrophilin 1 anticorps (AA 561-610)

N° du produit ABIN1535765

Cet anticorps anti-Latrophilin 1 Polyclonal Lapin (ABIN1535765) détecte spécifiquement Latrophilin 1 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Latrophilin 1 anticorps (AA 561-610) (ABIN1535765)

Antigène: Latrophilin 1 (LPHN1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Latrophilin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Latrophilin 1 anticorps

Épitope: AA 561-610

Fonction: Latrophilin-1 Antibody

Specificité: Latrophilin-1 Polyclonal Antibody detects endogenous levels of Latrophilin-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human LPHN1. AA range:561-610

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Latrophilin 1

Antigène: Latrophilin 1 (LPHN1)

Autre désignation: LPHN1

Sujet:

Synonyms: LPHN1, KIAA0821, LEC2, Latrophilin-1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Lectomedin-2

Background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008],

Gene Name: LPHN1

Protein Name: Latrophilin-1

Poids moléculaire: 162 kDa

ID gène: 22859

UniProt: O94910

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis