AVPR1B anticorps (AA 275-324)

N° du produit ABIN1536013

L’anticorps anti-AVPR1B Polyclonal Lapin est utilisé pour la détection de AVPR1B dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour AVPR1B anticorps (AA 275-324) (ABIN1536013)

Antigène: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AVPR1B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-AVPR1B anticorps

Épitope: AA 275-324

Fonction: AVP Receptor V3 Antibody

Specificité: AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur AVPR1B

Antigène: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Autre désignation: AVPR1B

Sujet:

Synonyms: AVPR1B, AVPR3, VPR3, Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor

Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],

Gene Name: AVPR1B

Protein Name: Vasopressin V1b receptor

Poids moléculaire: 46 kDa

ID gène: 553

OMIM: 600264

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones