AVPR2 anticorps (AA 72-121)

N° du produit ABIN1536014

Cet anticorps anti-AVPR2 Polyclonal Lapin (ABIN1536014) détecte spécifiquement AVPR2 dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AVPR2 anticorps (AA 72-121) (ABIN1536014)

Antigène: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AVPR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-AVPR2 anticorps

Épitope: AA 72-121

Fonction: AVP Receptor V2 Antibody

Specificité: AVP Receptor V2 Polyclonal Antibody detects endogenous levels of AVP Receptor V2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human AVPR2. AA range:72-121

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur AVPR2

Antigène: AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))

Autre désignation: AVPR2

Sujet:

Synonyms: AVPR2, ADHR, DIR, DIR3, V2R, Vasopressin V2 receptor, V2R, AVPR V2, Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor

Background: This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus

Gene Name: AVPR2

Protein Name: Vasopressin V2 receptor

Poids moléculaire: 40 kDa

ID gène: 554

OMIM: 300538

UniProt: P30518

Pathways: cAMP Metabolic Process