Coagulation Factor X anticorps (Cleaved-Ile235)

N° du produit ABIN486716

L’anticorps anti-Coagulation Factor X Polyclonal Lapin est utilisé pour la détection de Coagulation Factor X dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour Coagulation Factor X anticorps (Cleaved-Ile235) (ABIN486716)

Antigène: Coagulation Factor X (F10)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coagulation Factor X est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Coagulation Factor X anticorps

Épitope: AA 216-265, Cleaved-Ile235

Fonction: Cleaved-Factor Xa activated HC (I235) Antibody

Specificité: Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody detects endogenous levels of fragment of activated Factor Xa activated HC protein resulting from cleavage adjacent to I235.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human FA10. AA range:216-265

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Coagulation Factor X

Antigène: Coagulation Factor X (F10)

Autre désignation: FA10

Sujet:

Synonyms: F10, Coagulation factor X, Stuart factor, Stuart-Prower factor

Background: This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative sp

Gene Name: F10

Protein Name: Coagulation factor X

Poids moléculaire: 30 kDa

ID gène: 2159

OMIM: 227600

UniProt: P00742