CPT1C anticorps (Cleaved-Thr288)

N° du produit ABIN1536112

L’anticorps anti-CPT1C Polyclonal Lapin est utilisé pour la détection de CPT1C dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour CPT1C anticorps (Cleaved-Thr288) (ABIN1536112)

Antigène: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPT1C est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CPT1C anticorps

Épitope: AA 239-288, Cleaved-Thr288

Fonction: Cleaved-Cathepsin L1 HC (T288) Antibody

Specificité: Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L1 HC protein resulting from cleavage adjacent to T288.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CATL1. AA range:239-288

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CPT1C

Antigène: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Autre désignation: CATL1

Sujet:

Synonyms: CTSL1, CTSL, Cathepsin L1, Major excreted protein, MEP

Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012],

Gene Name: CTSL1

Protein Name: Cathepsin L1

Poids moléculaire: 30 kDa

ID gène: 1514

OMIM: 116880

UniProt: P07711

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process