MMP15 anticorps (Cleaved-Tyr132)

N° du produit ABIN1536143

Cet anticorps anti-MMP15 Polyclonal Lapin (ABIN1536143) détecte spécifiquement MMP15 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Singe.

Aperçu rapide pour MMP15 anticorps (Cleaved-Tyr132) (ABIN1536143)

Antigène: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP15 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MMP15 anticorps

Épitope: AA 113-162, Cleaved-Tyr132

Fonction: Cleaved-MMP-15 (Y132) Antibody

Specificité: Cleaved-MMP-15 (Y132) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-15 protein resulting from cleavage adjacent to Y132.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MMP15. AA range:113-162

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MMP15

Antigène: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Autre désignation: MMP15

Sujet:

Synonyms: MMP15, Matrix metalloproteinase-15, MMP-15, Membrane-type matrix metalloproteinase 2, MT-MMP 2, MTMMP2, Membrane-type-2 matrix metalloproteinase, MT2-MMP, MT2MMP, SMCP-2

Background: This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016],

Gene Name: MMP15

Protein Name: Matrix metalloproteinase-15

Poids moléculaire: 61 kDa

ID gène: 4324

OMIM: 602261

UniProt: P51511