MMP17 anticorps (Cleaved-Gln129)

N° du produit ABIN1536144

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP17 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MMP17 anticorps (Cleaved-Gln129) (ABIN1536144)

Antigène: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP17 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MMP17 anticorps

Épitope: AA 110-159, Cleaved-Gln129

Fonction: Cleaved-MMP-17 (Q129) Antibody

Specificité: Cleaved-MMP-17 (Q129) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-17 protein resulting from cleavage adjacent to Q129.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MMP17. AA range:110-159

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MMP17

Antigène: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Autre désignation: MMP17

Sujet:

Synonyms: MMP17, MT4MMP, Matrix metalloproteinase-17, MMP-17, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP

Background: This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers. [provided by RefSeq, Jan 2016],

Gene Name: MMP17

Protein Name: Matrix metalloproteinase-17

Poids moléculaire: 53 kDa

ID gène: 4326

OMIM: 602285

UniProt: Q9ULZ9