CASC5 anticorps (C-Term)

N° du produit ABIN1536748

Cet anticorps Lapin Polyclonal détecte spécifiquement CASC5 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour CASC5 anticorps (C-Term) (ABIN1536748)

Antigène: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASC5 est non-conjugé

Application: Western Blotting (WB)

Clone: RB40173

Détail du produit anti-CASC5 anticorps

Épitope: AA 1557-1583, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Mouse Casc5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur CASC5

Antigène: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Autre désignation: Casc5

Sujet: Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).

ID gène: 76464

UniProt: Q66JQ7

Pathways: Maintenance of Protein Location, Autophagy