TEF anticorps (C-Term)

N° du produit ABIN1536856

Cet anticorps Lapin Polyclonal détecte spécifiquement TEF dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TEF anticorps (C-Term) (ABIN1536856)

Antigène: TEF (Thyrotrophic Embryonic Factor (TEF))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEF est non-conjugé

Application: Western Blotting (WB)

Clone: RB39904

Détail du produit anti-TEF anticorps

Épitope: AA 213-240, C-Term

Homologie: C, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the C-terminal region of human TEF.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TEF Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur TEF

Antigène: TEF (Thyrotrophic Embryonic Factor (TEF))

Autre désignation: TEF

Sujet: Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP), VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Poids moléculaire: 33248

ID gène: 7008

NCBI Accession: NP_001138870, NP_003207

UniProt: Q10587