Apoptosis Inhibitor 5 anticorps (C-Term)
Aperçu rapide pour Apoptosis Inhibitor 5 anticorps (C-Term) (ABIN1537392)
Antigène
Voir toutes Apoptosis Inhibitor 5 (API5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 482-510, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This API5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-510 amino acids from the C-terminal region of human API5.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- API5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- Apoptosis Inhibitor 5 (API5)
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Autre désignation
- API5
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Sujet
- Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
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Poids moléculaire
- 59005
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ID gène
- 8539
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NCBI Accession
- NP_001136402, NP_001136403, NP_001230676, NP_006586
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UniProt
- Q9BZZ5
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Pathways
- Growth Factor Binding
Antigène
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