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FBXL19 anticorps (C-Term)

FBXL19 Reactivité: Humain WB Hôte: Lapin Polyclonal RB38770 unconjugated
N° du produit ABIN1537454
  • Antigène Voir toutes FBXL19 Anticorps
    FBXL19 (F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))
    Épitope
    • 9
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 543-570, C-Term
    Reactivité
    • 24
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 23
    • 1
    Lapin
    Clonalité
    • 23
    • 1
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp FBXL19 est non-conjugé
    Application
    • 18
    • 17
    • 2
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.
    Clone
    RB38770
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FBXL19 Anticorps primaire
  • Indications d'application
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    FBXL19 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Date de péremption
    6 months
  • Dong, Zhao, Wei, Bowser, Khoo, Liu, Luketich, Pennathur, Ma, Zhao: "F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation." dans: Molecular cancer, Vol. 13, pp. 76, (2014) (PubMed).

    Wei, Mialki, Dong, Khoo, Mallampalli, Zhao, Zhao: "A new mechanism of RhoA ubiquitination and degradation: Roles of SCF(FBXL19) E3 ligase and Erk2." dans: Biochimica et biophysica acta, (2013) (PubMed).

    Zhao, Mialki, Wei, Coon, Zou, Chen, Mallampalli, Zhao: "SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 7, pp. 2611-9, (2013) (PubMed).

  • Antigène
    FBXL19 (F-Box and Leucine-Rich Repeat Protein 19 (FBXL19))
    Autre désignation
    FBXL19 (FBXL19 Produits)
    Synonymes
    anticorps Fbl19, anticorps JHDM1C, anticorps 6030430O11, anticorps BC059812, anticorps F-box and leucine rich repeat protein 19, anticorps F-box and leucine-rich repeat protein 19, anticorps F-box and leucine-rich repeat protein 19 S homeolog, anticorps F-box/LRR-repeat protein 19, anticorps FBXL19, anticorps Fbxl19, anticorps fbxl19.S, anticorps LOC540981, anticorps LOC100431704
    Sujet
    Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
    Poids moléculaire
    75707
    ID gène
    54620
    NCBI Accession
    NP_001093254, NP_001269280
    UniProt
    Q6PCT2
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