TOP3B anticorps (C-Term)
Aperçu rapide pour TOP3B anticorps (C-Term) (ABIN1537618)
Antigène
Voir toutes TOP3B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 826-854, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This TOP3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-854 amino acids from the C-terminal region of human TOP3B.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- TOP3B Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
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Autre désignation
- TOP3B
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Sujet
- This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity, however, not all variants have been fully described.
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Poids moléculaire
- 96662
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ID gène
- 8940
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NCBI Accession
- NP_001269041, NP_001269042, NP_003926
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UniProt
- O95985
Antigène
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