Catalase anticorps (AA 152-180)

N° du produit ABIN1537700

L’anticorps Souris Monoclonal anti-Catalase a été validé pour WB. Il convient pour détecter Catalase dans des échantillons de Humain et Souris. Il y a 1 publication disponible.

Aperçu rapide pour Catalase anticorps (AA 152-180) (ABIN1537700)

Antigène: Catalase (CAT)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Catalase est non-conjugé

Application: Western Blotting (WB)

Clone: 626CT4-3-8

Détail du produit anti-Catalase anticorps

Épitope: AA 152-180

Homologie: B, Zf, Pig, Rat

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This CAT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT.

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:1600. WB: 1:1600

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: CAT Antibody (Center)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-Catalase (ABIN1537700)

Pereira, Igea, Canovas, Dolado, Nebreda: "Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK." dans: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1759-74, (2013) (PubMed).

Détails sur Catalase

Antigène: Catalase (CAT)

Autre désignation: CAT

Sujet: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Poids moléculaire: 59756

ID gène: 847

NCBI Accession: NP_001743

UniProt: P04040

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism