PCBP1 anticorps (AA 188-217)

N° du produit ABIN1538004

Détail du produit anti-PCBP1 anticorps

Antigène: PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

Épitope: AA 188-217

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCBP1 est non-conjugé

Application: Western Blotting (WB)

Homologie: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PCBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the Central region of human PCBP1.

Clone: RB39472

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PCBP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur PCBP1

Antigène: PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

Autre désignation: PCBP1 (PCBP1 Produits)

Synonymes: anticorps PCBP1, anticorps HNRPE1, anticorps HNRPX, anticorps hnRNP-E1, anticorps hnRNP-X, anticorps hnRNP E1, anticorps WBP17, anticorps [a]CP-1, anticorps alphaCP-1, anticorps RGD1561319, anticorps poly(rC) binding protein 1, anticorps poly(rC) binding protein 1 L homeolog, anticorps poly(rC)-binding protein 1, anticorps PCBP1, anticorps pcbp1.L, anticorps LOC100388387, anticorps Pcbp1

Sujet: This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

Poids moléculaire: 37498

ID gène: 5093

NCBI Accession: NP_006187

UniProt: Q15365