Coagulation Factor IX anticorps (AA 266-295)
Aperçu rapide pour Coagulation Factor IX anticorps (AA 266-295) (ABIN1538212)
Antigène
Voir toutes Coagulation Factor IX (F9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 266-295
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This F9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the Central region of human F9.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000. WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- F9 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- Coagulation Factor IX (F9)
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Autre désignation
- F9
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Sujet
- This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
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Poids moléculaire
- 51778
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ID gène
- 2158
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NCBI Accession
- NP_000124
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UniProt
- P00740
Antigène
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