PPP1R16B anticorps (AA 372-399)
Aperçu rapide pour PPP1R16B anticorps (AA 372-399) (ABIN1538368)
Antigène
Voir toutes PPP1R16B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 372-399
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Homologie
- B, M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This PPP1R16B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-399 amino acids from the Central region of human PPP1R16B.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- PPP1R16B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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: "Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells." dans: The international journal of biochemistry & cell biology, Vol. 82, pp. 10-17, (2017) (PubMed).
: "PKC mediated phosphorylation of TIMAP regulates PP1c activity and endothelial barrier function." dans: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 2, pp. 431-439, (2017) (PubMed).
: "TIMAP-protein phosphatase 1-complex controls endothelin-1 production via ECE-1 dephosphorylation." dans: The international journal of biochemistry & cell biology, Vol. 73, pp. 11-18, (2016) (PubMed).
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: "Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells." dans: The international journal of biochemistry & cell biology, Vol. 82, pp. 10-17, (2017) (PubMed).
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- PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))
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Autre désignation
- PPP1R16B
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Sujet
- The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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Poids moléculaire
- 63551
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ID gène
- 26051
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NCBI Accession
- NP_001166206, NP_056383
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UniProt
- Q96T49
Antigène
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