Cet anticorps Lapin Polyclonal détecte spécifiquement PPP1R16B dans WB. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 3+ publications.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This PPP1R16B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-399 amino acids from the Central region of human PPP1R16B.
PPP1R16B
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
PPP1R16B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Date de péremption
6 months
Boratkó, Péter, Csortos: "Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells." dans: The international journal of biochemistry & cell biology, Vol. 82, pp. 10-17, (2017) (PubMed).
Boratkó, Csortos: "PKC mediated phosphorylation of TIMAP regulates PP1c activity and endothelial barrier function." dans: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 2, pp. 431-439, (2017) (PubMed).
Boratkó, Veréb, Petrovski, Csortos: "TIMAP-protein phosphatase 1-complex controls endothelin-1 production via ECE-1 dephosphorylation." dans: The international journal of biochemistry & cell biology, Vol. 73, pp. 11-18, (2016) (PubMed).
The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.