RNF144B anticorps (AA 90-118)

N° du produit ABIN1538681

Détail du produit anti-RNF144B anticorps

Antigène: RNF144B (Ring Finger Protein 144B (RNF144B))

Épitope: AA 90-118

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF144B est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RNF144B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of human RNF144B.

Clone: RB37984

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RNF144B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur RNF144B

Antigène: RNF144B (Ring Finger Protein 144B (RNF144B))

Autre désignation: RNF144B (RNF144B Produits)

Synonymes: anticorps IBRDC2, anticorps PIR2, anticorps bA528A10.3, anticorps p53RFP, anticorps BC025007, anticorps E130105P19Rik, anticorps Ibrdc2, anticorps Pir2, anticorps ring finger protein 144B, anticorps RNF144B, anticorps Rnf144b

Sujet: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death, But, it is not an anti-apoptotic protein per se.

Poids moléculaire: 33697

ID gène: 255488

NCBI Accession: NP_877434

UniProt: Q7Z419