EXOSC6 anticorps (N-Term)

N° du produit ABIN1538987

L’anticorps Lapin Polyclonal anti-EXOSC6 a été validé pour WB. Il convient pour détecter EXOSC6 dans des échantillons de Humain.

Aperçu rapide pour EXOSC6 anticorps (N-Term) (ABIN1538987)

Antigène: EXOSC6 (Exosome Component 6 (EXOSC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOSC6 est non-conjugé

Application: Western Blotting (WB)

Clone: RB39844

Détail du produit anti-EXOSC6 anticorps

Épitope: AA 12-38, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EXOSC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-38 amino acids from the N-terminal region of human EXOSC6.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: EXOSC6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur EXOSC6

Antigène: EXOSC6 (Exosome Component 6 (EXOSC6))

Autre désignation: EXOSC6

Sujet: This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.

Poids moléculaire: 28235

ID gène: 118460

NCBI Accession: NP_478126

UniProt: Q5RKV6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response