This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This RANBP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from the N-terminal region of human RANBP17.
anticorps RGD1562576, anticorps RANBP17, anticorps 4932704E15Rik, anticorps RAN binding protein 17, anticorps Ranbp17, anticorps RANBP17, anticorps ranbp17
Sujet
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex, see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.