Calsyntenin 1 anticorps (N-Term)

N° du produit ABIN1539080

L’anticorps Lapin Polyclonal anti-Calsyntenin 1 a été validé pour WB. Il convient pour détecter Calsyntenin 1 dans des échantillons de Humain.

Aperçu rapide pour Calsyntenin 1 anticorps (N-Term) (ABIN1539080)

Antigène: Calsyntenin 1 (CLSTN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calsyntenin 1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB38737

Détail du produit anti-Calsyntenin 1 anticorps

Épitope: AA 15-42, N-Term

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CLSTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human CLSTN1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: CLSTN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur Calsyntenin 1

Antigène: Calsyntenin 1 (CLSTN1)

Autre désignation: CLSTN1

Sujet: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity).

Poids moléculaire: 109793

ID gène: 22883

NCBI Accession: NP_001009566, NP_055759

UniProt: O94985