RCAN1 anticorps (N-Term)
Aperçu rapide pour RCAN1 anticorps (N-Term) (ABIN1539360)
Antigène
Voir toutes RCAN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 41-68, N-Term
-
Homologie
- M
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogène
- This RCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- IF: 1:10~50. WB: 1:1000. WB: 1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- RCAN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
-
Date de péremption
- 6 months
-
-
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
-
Autre désignation
- RCAN1
-
Sujet
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
-
Poids moléculaire
- 28079
-
ID gène
- 1827
-
NCBI Accession
- NP_004405, NP_981962, NP_981963
-
UniProt
- P53805
-
Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
-