SPRY2 anticorps (N-Term)

N° du produit ABIN1539429

Détail du produit anti-SPRY2 anticorps

Antigène: SPRY2 (Sprouty Homolog 2 (SPRY2))

Épitope: AA 6-35, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPRY2 est non-conjugé

Application: Western Blotting (WB)

Homologie: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SPRY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human SPRY2.

Clone: RB36778

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SPRY2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur SPRY2

Antigène: SPRY2 (Sprouty Homolog 2 (SPRY2))

Autre désignation: SPRY2 (SPRY2 Produits)

Synonymes: anticorps wu:fk66h11, anticorps wu:fk93e11, anticorps zgc:110440, anticorps hspry2, anticorps xspry2, anticorps sprouty2, anticorps Xsprouty2, anticorps sprouty-2, anticorps Xtsprouty2, anticorps hSPRY2, anticorps sprouty RTK signaling antagonist 2, anticorps sprouty RTK signaling antagonist 2 S homeolog, anticorps sprouty homolog 2 (Drosophila), anticorps spry2, anticorps SPRY2, anticorps spry2.S, anticorps Spry2

Sujet: This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq].

Poids moléculaire: 34688

ID gène: 10253

NCBI Accession: NP_005833

UniProt: O43597

Pathways: EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation