B-Cell Linker anticorps (AA 150-178)
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- Antigène Voir toutes B-Cell Linker (BLNK) Anticorps
- B-Cell Linker (BLNK)
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Épitope
- AA 150-178
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp B-Cell Linker est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogène
- This BLNK antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from human BLNK.
- Clone
- 520CT6-1-1
- Isotype
- IgM
- Top Product
- Discover our top product BLNK Anticorps primaire
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- Indications d'application
- WB: 1:500~8000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- BLNK Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- B-Cell Linker (BLNK)
- Autre désignation
- BLNK (BLNK Produits)
- Synonymes
- anticorps BLNK, anticorps blnk, anticorps MGC147045, anticorps BASH, anticorps Bca, anticorps Ly-57, anticorps Ly57, anticorps Lyw-57, anticorps SLP-65, anticorps AGM4, anticorps BLNK-S, anticorps LY57, anticorps SLP65, anticorps bca, anticorps B-cell linker, anticorps B cell linker, anticorps BLNK, anticorps blnk, anticorps Blnk
- Sujet
- This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 50466
- ID gène
- 29760
- NCBI Accession
- NP_001107566, NP_001245369, NP_037446
- UniProt
- Q8WV28
- Pathways
- BCR Signaling
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