IgD anticorps (N-Term)

N° du produit ABIN1539994

Cet anticorps Souris Monoclonal détecte spécifiquement IgD dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour IgD anticorps (N-Term) (ABIN1539994)

Antigène: IgD

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IgD est non-conjugé

Application: Western Blotting (WB)

Clone: 607CT8-4-4

Détail du produit anti-IgD anticorps

Épitope: AA 37-64, N-Term

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This IGHD antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-64 amino acids from the N-terminal region of human IGHD.

Isotype: IgM

Information d'application

Indications d'application: WB: 1:100~800

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: IGHD Antibody (N-term)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur IgD

Antigène: IgD

Autre désignation: IGHD

Classe de substances: Antibody

Sujet: IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.

Poids moléculaire: 42353

ID gène: 3495

UniProt: P01880