Vitamin D Receptor anticorps

N° du produit ABIN1540015

Cet anticorps Lapin Polyclonal détecte spécifiquement Vitamin D Receptor dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Vitamin D Receptor anticorps (ABIN1540015)

Antigène: Vitamin D Receptor (VDR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vitamin D Receptor est non-conjugé

Application: Western Blotting (WB)

Clone: RB38491

Détail du produit anti-Vitamin D Receptor anticorps

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This VDR antibody is generated from rabbits immunized with a recombinant protein of human VDR.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: VDR Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur Vitamin D Receptor

Antigène: Vitamin D Receptor (VDR)

Autre désignation: VDR

Classe de substances: Chemical

Sujet: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.

Poids moléculaire: 48289

ID gène: 7421

NCBI Accession: NP_000367, NP_001017535, NP_001017536

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway