HMOX2 anticorps
Aperçu rapide pour HMOX2 anticorps (ABIN155125)
Antigène
Voir toutes HMOX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- The antibody recognizes ~36 kDa Heme-Oxygenase-2.
-
Purification
- Immunoaffinity purified
-
Immunogène
- Synthetic peptide surrounding amino acid 25 of human HO-2
-
-
-
-
Indications d'application
-
Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry on frozen sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- -20 °C/-80 °C
-
Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
-
-
- HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))
-
Autre désignation
- Heme Oxygenase 2 (HMOX2)
-
Sujet
- Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two heme oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. At the amino acid level, HO-1 and HO-2 are 42 % homologous. However, each isozyme is evolutionary highly conserved. HO-1 is the inducible form of the enzyme and is therefore also referred to as stress protein Hsp32. Expression of HO-1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO-2 is the constituitive form of the enzyme. It is not inducible by exogeneous stimuli and HO-2 is the most prevalent form in most tissues, except the spleen where HO-1 levels are predominant under normal conditions.Synonyms: HO-2, HO2
-
ID gène
- 3163
-
NCBI Accession
- NP_001120676
-
UniProt
- P30519
-
Pathways
- Transition Metal Ion Homeostasis
Antigène
-