Fc epsilon RI/FCER1A anticorps
Aperçu rapide pour Fc epsilon RI/FCER1A anticorps (ABIN1558257)
Antigène
Voir toutes Fc epsilon RI/FCER1A (FCER1A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- The antibody recognizes an epitope within the a2 domain of the human high affinity IgE receptor (FceRIa). It inhibits binding of IgE to this receptor and is suitable to detect receptors expressed on primary cells and cell lines (e.g mast cells and basophils). It can also be used as weak to moderate cross-linking agent for IgE-independent triggering of effector cells and to detect FceRIa in ELISA and W-blots.
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Purification
- Affinity - purified from cell culture supernatant by Immunoaffinity Chromatography on anti-mouse IgG1 agarose
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Pureté
- 98 % (Gel Permeation Chromatography)
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Stérilité
- Sterile filtered
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Immunogène
- Recombinant human FCER1A
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Isotype
- IgG1 kappa
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Indications d'application
- Can be used for functional mast cell / basophil assays
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH=7.2, 0.1 % NaN3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8°C. For long term storage, aliquot and store at -20°C or -80°C
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Autre désignation
- FCER1A
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Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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