Peripherin anticorps

N° du produit ABIN4956261

L’anticorps Souris Monoclonal anti-Peripherin a été validé pour WB, IHC, IF et ICC. Il convient pour détecter Peripherin dans des échantillons de Mammifères.

Aperçu rapide pour Peripherin anticorps (ABIN4956261)

Antigène: Peripherin (PRPH)

Reactivité: Mammifères

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Peripherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 7C5

Détail du produit anti-Peripherin anticorps

Purification: purified

Isotype: IgG1

Information d'application

Indications d'application: MCA-7C5 is supplied as 500 µLs of concentrated tissue culture supernatant. For immunocytochemistry we recommend dilutions of 1:200, and for western blot 1:1,000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4°C. For safest long-term storage, maintain aliquots at -80°C or -20°C. Avoid repeated freeze-thaw cycles.

Détails sur Peripherin

Antigène: Peripherin (PRPH)

Autre désignation: Peripherin

Sujet: Peripherin is a approx. 57 kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. The HGNC name for this protein is PRPH. Subsequently peripherin was found in some sensory and other neurons of the central nervous system and also in rat pheochromacytoma PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration. The characterization of an antibody very similar to MCA-7C5 has been published. The HGNC name for this protein is PRPH.