PLGF anticorps

N° du produit ABIN1589795

Cet anticorps Lapin Polyclonal détecte spécifiquement PLGF dans IHC. Il présente une réactivité envers Souris.

Aperçu rapide pour PLGF anticorps (ABIN1589795)

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLGF est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-PLGF anticorps

Fonction: PlGF antibody

Specificité: Recombinant mouse PlGF

Attributs du produit: Chromosomal location: 12 D, 12 39.0 cM
Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

Purification: Protein A purified

Immunogène: Recombinant mouse PlGF (ABIN1589564)

Isotype: IgG

Information d'application

Indications d'application: Use 1:200

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: 0.5X PBS

Conseil sur la manipulation: Centrifuge vial prior to opening.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Date de péremption: 24 months

Détails sur PLGF

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Autre désignation: PlGF

Sujet: Pgf, PlGF, Plgf, AI854365, placental growth factor,Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65 % amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.

ID gène: 18654

NCBI Accession: NM_008827, NP_032853

UniProt: P49764

Pathways: VEGFR1 Specific Signals