LGALS1/Galectin 1 anticorps

N° du produit ABIN1589812

Cet anticorps anti-LGALS1/Galectin 1 Polyclonal Lapin (ABIN1589812) détecte spécifiquement LGALS1/Galectin 1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour LGALS1/Galectin 1 anticorps (ABIN1589812)

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGALS1/Galectin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LGALS1/Galectin 1 anticorps

Fonction: Rabbit Anti-Human Galectin-1 Polyclonal Antibody

Specificité: Recombinant human Galectin-1

Attributs du produit: Chromosomal location: 22q13.1

Purification: Protein A purified

Immunogène: Recombinant human Galectin-1 ()

Isotype: IgG

Information d'application

Indications d'application: Western Blot: Use 1-5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: 3 mM PBS, pH 7.2

Conseil sur la manipulation: Centrifuge vial prior to opening.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Date de péremption: 24 months

Détails sur LGALS1/Galectin 1

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Autre désignation: Galectin-1

Sujet:

Synonyms: LGALS1, GBP, GAL1

Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88 % amino acid sequence similarity.

ID gène: 3956

NCBI Accession: NM_002305, NP_002296

UniProt: P09382

Pathways: Carbohydrate Homeostasis