HTRA2 anticorps (S306A)

N° du produit ABIN165414

Cet anticorps anti-HTRA2 est un anticorps Souris Monoclonal détectant HTRA2 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour HTRA2 anticorps (S306A) (ABIN165414)

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HTRA2 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1B3

Détail du produit anti-HTRA2 anticorps

Épitope: AA 134-458, S306A

Fonction: Human HTRA2/OMI (S306A) antibody

Purification: Purified

Immunogène: Recombinant human HtrA2/Omi (134-458aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Indications d'application: Recommended dilution 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur HTRA2

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Autre désignation: HTRA2/OMI

Sujet: HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain, an inhibitor of apoptosis protein (IAP) -binding motif, a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death.

NCBI Accession: NP_037379

Pathways: Positive Regulation of Endopeptidase Activity