NCR1 anticorps (AA 22-255)

N° du produit ABIN165440

L’anticorps anti-NCR1 Monoclonal produit chez le Souris a été validé pour WB, FACS et ELISA. Il convient pour la détection de NCR1 dans des échantillons provenant de Humain. }

Aperçu rapide pour NCR1 anticorps (AA 22-255) (ABIN165440)

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Clone: N1D9

Détail du produit anti-NCR1 anticorps

Épitope: AA 22-255

Fonction: Human NKp46/NCR1 antibody

Purification: Purified

Immunogène: Recombinant human Nkp46 (22-255aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur NCR1

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: NKp46/NCR1

Sujet: A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

NCBI Accession: NP_004820

Pathways: Regulation of Leukocyte Mediated Immunity