Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 1-220) anticorps
Aperçu rapide pour Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (AA 1-220) anticorps (ABIN1678521)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-220
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Séquence
- MAAGFGRCCR VLRSISRFHW RSQHTKANRQ REPGLGFSFE FTEQQKEFQA TARKFAREEI IPVAAEYDKT GEYPVPLIRR AWELGLMNTH IPENCGGLGL GTFDACLISE ELAYGCTGVQ TAIEGNSLGQ MPIIIAGNDQ QKKKYLGRMT EEPLMCAYCV TEPGAGSDVA GIKTKAEKKG DEYIINGQKM WITNGGKANW YFLLARSDPD PKAPANKAFT
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACADM (NP_000007.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." dans: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).
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- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)
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Autre désignation
- ACADM
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Sujet
- This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ACADM,ACAD1,MCAD,MCADH,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,ACADM
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Poids moléculaire
- 46 kDa/47 kDa
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ID gène
- 34
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UniProt
- P11310
Antigène
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