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BIN1 anticorps (AA 230-409)

BIN1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1678863
  • Antigène Voir toutes BIN1 Anticorps
    BIN1 (Bridging Integrator 1 (BIN1))
    Épitope
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 230-409
    Reactivité
    • 47
    • 24
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 33
    • 13
    • 1
    Lapin
    Clonalité
    • 34
    • 13
    Polyclonal
    Conjugué
    • 33
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BIN1 est non-conjugé
    Application
    • 35
    • 22
    • 19
    • 9
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Séquence
    QNLNDVLVGL EKQHGSNTFT VKAQPSDNAP AKGNKSPSPP DGSPAATPEI RVNHEPEPAG GATPGATLPK SPSQSSLPAV VVETFPATVN GTVEGGSGAG RLDLPPGFMF KVQAQHDYTA TDTDELQLKA GDVVLVIPFQ NPEEQDEGWL MGVKESDWNQ HKELEKCRGV FPENFTERVP
     Réactivité croisée
    Humain, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 230-409 of human BIN1 (NP_647601.1).
    Isotype
    IgG
    Top Product
    Discover our top product BIN1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:20 - 1:50
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    BIN1 (Bridging Integrator 1 (BIN1))
    Autre désignation
    BIN1 (BIN1 Produits)
    Synonymes
    anticorps bin1, anticorps MGC53185, anticorps amph2, anticorps amphl, anticorps sh3p9, anticorps MGC76187, anticorps cb57, anticorps zgc:86701, anticorps BIN1, anticorps AMPH2, anticorps AMPHL, anticorps SH3P9, anticorps ALP-1, anticorps Amphl, anticorps BRAMP-2, anticorps bridging integrator 1, anticorps bridging integrator 1 S homeolog, anticorps bridging integrator 1b, anticorps BIN1, anticorps bin1.S, anticorps bin1, anticorps bin1b, anticorps Bin1
    Sujet
    This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.,BIN1,AMPH2,AMPHL,SH3P9,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,BIN1
    Poids moléculaire
    45-64 kDa
    ID gène
    274
    UniProt
    O00499
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